"The mRNA vaccine is injected intramuscularly through the arm. This method is preferredbecause large muscle cells have high vascularity, so the injected biomaterial can easily reach the systemic bloodstream and lymphatic system.
LNPs fuse with and enter mammalian cells easily. As mentioned, the Pfizer-BioNTech and Moderna mRNA vaccines use LNPs to encapsulate the mRNA genetic material for more efficient cell delivery.
Thus, the combined intramuscular injection and LNP technology would enable the mRNA vaccine to reach a broad range of cell types. The mRNA might even reach delicate cells or places that we don't want them to, such as neurons in the brain or spinal cord."
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